News
Animal testing in drug development is no longer an absolute requirement in US: are we ready to replace (completely) animal testing by pharmaceutical data-intelligence and in-vitro systems? (Ref.)
In our recent publication green chemistry principles were applied to the preparation of an analytical reagent. The functionality and cost-efficiency were included to evaluate sustainability. A Derringer desirability function was used to obtain a sustainability score. Replacing acetonitrile by ethanol resulted in the most sustainable reagent. Other factors were of less influence on the total desirability or sustainability.
Click here to read the article for free during the first 50 days after publication!
As a consequence of the FDA Reauthorization Act of 2017, a draft guidance about competitive generic therapy (CGT) is published with the aim to incentivize generic competition in USA. The designation of medicine as CGT, the request for designation, the expedited review and the 180 days exclusivity period are explained in this draft guideline (rev.1). Although improvements and clarifications can certainly be made to the current version, it certainly makes medicines more affordable as part of their overall sustainability.
On Monday, September 19th, the very first group of S-DISCO students started their journey of learning and sharing knowledge with the summer school at GhentUniversity. The summer school is packed with introductory sessions to prepare them for the official start of lectures. Throughout the week, the students had the opportunity to get to know the university, the lecturers from the different consortium partners, and most importantly their fellow students! We are off to a great start and wish everyone involved a productive and enjoyable master’s program.
More info on the S-DISCO website.
EMA and the Heads of Medicines Agencies (HMA) have recently issued a joint statement confirming that biosimilar medicines approved in the European Union (EU) are interchangeable with their reference medicine or with an equivalent biosimilar.
https://www.ema.europa.eu/en/news/biosimilar-medicines-can-be-interchanged
The annual JCR release by Clarivate analytics enables the research community to evaluate the world’s high-quality academic journals using a range of indicators, descriptive data and visualizations. This year’s JCR release is based on 2021 data compiled from the Web of Science Core Collection™.
The latest Journal Impact Factor of Journal of Pharmaceutical Analysis (JPA) is 14.026, and DruQuaR (UGent) is proud of being part of it from the beginning with prof. Bart De Spiegeleer as one of the associate editors.
On 28 June 2022, the 3rd bachelor students in Pharmaceutical Sciences presented the results of their bachelor thesis to an interdisciplinary jury. Through a poster presentation, the students had to opportunity to display and discuss their experiments performed in the different research labs of the faculty. Photo's can be viewed here.
Ghent University (Belgium), the Medical University of Gdansk (Poland), the University of Groningen (The Netherlands) and the University of Lille (France) jointly announce the new Erasmus+ Mundus Joint Master Degree Programme in Sustainable Drug Discovery (acronym: S-DISCO). This EU partnership of the four universities was selected under Erasmus+ to provide funding for talented students attending the course.
This programme originates from longstanding informal discussions between some of the partners on the need to train students in drug discovery, the challenging phase in the life cycle of a medicine that precedes first-in-human studies and clinical development. The programme is unique in that it will pay notable attention to sustainability, an aspect that currently receives little attention in traditional educational programmes in this area. Sustainability boundaries, including environmental, ecological and socio-economic dimensions, add an extra level of complexity to drug discovery, but are of increasing importance to competent authorities and the society at large.
Prof. Bart De Spiegeleer, prof. Serge Van Calenbergh and Dr. Evelien Wynendaele, from the Faculty of Pharmaceutical Sciences (with prof. Jan Van Bocxlaer as the dean), are the coordinators of this new international S-DISCO programme. It is a two-year Master programme consisting of logically aligned modules with stepwise build-up knowledge, skills and competences. By applying case-based learning, it will stimulate students to integrate, connect, confront and reconcile multi-perspective ways of looking at sustainable drug discovery.
After a preparative summer school in Ghent, all students will stay the first semester at this institution and the second semester in Gdansk. In the third semester, students may customize their studies in Lille or Groningen. In the fourth semester, students will perform a master thesis in one of these partner institutions or with one of the numerous associated partners (incl. industry, competent authorities and research institutions). Successful students will obtain a common master-degree of the 4 universities.
Scholarships from the EU will be available for on average 21 students every year, with both European and International students being invited to apply for the programme and associated grants. The grant covers the tuition fee, and also provides a travel and living allowance. Call for applications will be opened begin January 2022! The deadline for applications will be 28th February 2022. More information will soon appear on the course website.
Website of the International Master in Sustainable Drug Discovery
De studenten 3e Bachelor in de Farmaceutische Wetenschappen stelden hun resultaten van de Farmaceutische Bachelorproef voor aan een multidisciplinaire jury. Foto’s (link: https://photos.app.goo.gl/b1xxK1GUxqSSvRVV8)
De studenten 3e Bachelor in de Farmaceutische Wetenschappen stelden hun resultaten van de Farmaceutische Bachelorproef voor aan een multidisciplinaire jury. Foto’s (link: https://photos.app.goo.gl/f5GMhwCmnKxTtCPCA)
De studenten 3e Bachelor in de Farmaceutische Wetenschappen stelden hun resultaten van de Farmaceutische Bachelorproef voor aan een multidisciplinaire jury. jury op één lijn achter multidisciplinaire.
De studenten 3e Bachelor in de Farmaceutische Wetenschappen stelden hun resultaten van de Farmaceutische Bachelorproef voor aan een multidisciplinaire jury. Foto's
DruQuar kindly invites you to the seminar of prof. dr. Albert Gjedde (University of Copenhagen) on 25 August 2015 at 15h00 in seminar room 2 of the Faculty of Pharmaceutical Sciences. The topic of this seminar is "Kinetics of blood-brain transfert of molecules: From passive diffusion to active transport". On the link below you can find the abstract of his talk.
Albert Gjedde is (co-)author of a long list of highly cited publications like his work on the Gjedde-Patlak plot, also known as the Multitime Graphical Analysis, which linearized irreversible brain uptake of tracers. During his career, he has received pultiple academic distinctions for his pioneering work as neuroscientist.
We hope to welcome you on 25 August 2015 !
Postersessie FaBaP 2015 (June 2015)
Ook dit jaar stelden de studenten van de 3e Bachelor in de Farmaceutische Wetenschappen de resultaten van de Farmaceutische Bachelorproef voor aan de multidisciplinaire jury, die studenten kritische evalueerde. Foto's
Postersessie Farmaceutische bachelorproef 23 juni 2014 (June 2014)
Naar jaarlijkse gewoonte vond op maandag 23 juni 2014 de postersessie plaats. De studenten van de derde bachelor in de Farmaceutische Wetenschappen presenteerden er de bekomen resultaten van de Farmaceutische Bachelorproef en werden beoordeeld door een vakkundige jury, samengesteld uit zowel academici als mensen uit de farmaceutische sector in al zijn geledingen. Foto's
Gastsprekers tijdens lessen Registratie van geneesmiddelen (November 2013)
Drie gastsprekers werden uitgenodigd om een hoorcollege te geven in het vak Registratie (Master Geneesmiddelen Ontwikkeling).
1) Variaties (6 november 2013) door Ph.D. Bram Baert (Pfizer)
2) Prijs en terugbetaling (13 novermber 2013) door ind.apoth. Agnes Degroote (consultant)
3) Informatie en farmacovigilantie (20 november 2013): M.D. Christine Lenaerts (Roche).
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Lecture by David Craik: Discovery of naturally occuring cyclic peptides and their applications in drug design (July 2013)
On the 9th July 2013, professor David Craik from the Institute for Molecular Bioscience of the university of Queensland (Australia), was invited to give a lecture about his research, which focuses on the application of NMR in drug design and on toxins, including conotoxins. His group has a particular focus on structural studies of disulfide-rich proteins/peptides, and on the discovery and applications of circular and novel protein/peptide topologies. The presentation can be found by clicking here presentation
Quorumpeps® database (on web May 2012)
Quorumpeps® is a resource of quorum-sensing signalling peptides. This database is linked to a manuscript entitled "Quorumpeps database:chemical space and functionality of quorum-sensing peptides".(Nucleic Acids Research, accepted for publication), in which the origin of the different peptides and their quorum-sensing pathways and methods are described. The database is a collaboration project with the TELIN group of Ghent University.
Link to website : http://quorumpeps.ugent.be
Alkamid® database (on web March 2012)
Alkamid® is a resource of plant occuring N-alkamides (N-AAs). The Alkamid®database is coupled to a manuscript entitled "Alkamid database: Chemistry, occurrence and functionality of plant N-alkylamides" (Journal of Ethnopharmacology, doi: 10.1016/j.jep.2012.05.038), in which the origin of the different types N-alkylamide, their biosynthetic pathways and functionalities are described. The database is a collaboration project with the TELIN group of Ghent Unviversity.
Link to website : http://alkamid.ugent.be
Brainpeps® database (on web January 2012)
Brainpeps® is a resource of blood-brain barrier properties of peptides. The database is linked to the manuscript "Brainpeps: the blood-brain barrier petide database". (Brain Structure and Function, 217, 687-718), in which the BBB methods and responses are clarified and correlated to each other. The database is a collaboration project with the TELIN group of Ghent University.
Link to website : http://brainpeps.ugent.be